While these drugs were not initially approved for weight management, a small proportion of patients were using them to support weight loss, with doctors prescribing these off-label (off-label prescribing is where a drug is prescribed for a reason other than the one it is licensed for) in these cases, GLP-1RAs were given to people without diabetes but with a high body mass index (BMI)
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Why WADA Is Watching WADA evaluates substances against three criteria for prohibition: performance enhancement, health risk, and spirit of sport
A number of studies have demonstrated sustained weight loss post-medication removal
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Drug interactions and metabolism Weight loss associated with GLP-1R use may alter drug metabolism of weight-based medications (e.g., levothyroxine, warfarin )