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J Clin Endocrinol Metab 86:43304338 Goldstone AP, Thomas EL, Brynes AE, Castroman G, Edwards R, Ghatei MA, Frost G, Holland AJ, Grossman AB, Korbonits M et al (2004) Elevated fasting plasma ghrelin in PraderWilli syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance