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J Vet Pharmacol Ther 7 (3): 225-31(1984) Following distribution into tissues, rapidly reduced to leukomethylene blue (leucomethylthioninium chloride)

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The primary dietary contributors are animal foods

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2 It appeared to bind the same receptor

One primary challenge resides in catalases short half-life, poor cellular absorption, and the inherent difficulty in safely and effectively transporting the enzyme into tissues and systems like the central nervous system [181]