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These include: Drugs called H2 receptor antagonists Metformin Proton pump inhibitors

305 , E1309E1318 (2013)

Cells were harvested by centrifugation at 4,400 g at 4 C for 15 min and the medium was discarded

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A key finding was its ability to reduce phosphorylation of myosin light chain-2 through inhibition of the ROCK pathway, a central regulator of perijunctional actomyosin contraction and barrier leakiness

21,22 About obesity and overweight In 2016, more than 1.9 billion adults lived with overweight defined as a body mass index (BMI) of 25 or more