Thyroid function tests should also be done to rule out overt hypothyroidism as a cause of the patients symptoms.31,32 Various types of hypothyroid states exist, including the following: primary (disease of the thyroid gland itself), secondary or pituitary (from the lack of thyroid stimulating hormone), late Hashimotos thyroiditis (autoimmunity against the thyroid), iodine deficiency goiter, genetic thyroid enzyme defects, conversion of T4 to T3 defects, thyroid receptor insensitivity, and drug-induced hypothyroidism (ie, lithium, sulfonamides, phenylbutazone, or oral contraceptives).33-35 All of these disorders can result in a functional hypothyroidism and a very similar clinical presentation
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Tumor volumes were measured by Vernier caliper across 2 perpendicular diameters, and volumes were calculated according to the following formula: V = 4/3 [(d1 + d2)/4]3 where d1 and d2 are the 2 perpendicular diameters
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Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis
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