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While dietary fiber supports digestive health long-term, suddenly increasing fiber intake while starting semaglutide can worsen diarrhea

In the meantime, you can reduce your fatigue by trying a few simple lifestyle changesand if that doesnt work, work with your healthcare professional to adjust your dosage and scheduling

GLP-1 agonists work in several ways, such as by: stimulating meal-dependent insulin secretion by the pancreatic beta cells decreasing the secretion of glucagon, a hormone that raises blood sugar decreasing gastric emptying decreasing appetite and reducing food intake by creating a sensation of stomach fullness GLP-1 agonists may also have some direct effects on brain hunger centers

Thus, it increases circulating growth hormone and IGF-1

& Shindler, K

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