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Although the functions of granins are still being elucidated, secretoneurin has been shown to induce mucus hypersecretion in human airway epithelial cell lines (16HBE and NCI-H292) and induce expression of muc5AC [36], suggesting a modulatory role in mucus secretion

The cascade results in increased mitochondria-derived peptide MOTS-c expression, thus forming a loop that may regulate the expression of osteoblast or osteoclast-related genes

First, retatrutide requires larger injection volumes at maintenance doses

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Skyline output files and calibration range tables are provided in the Source Data file

Proteomics QC