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Strategies for breaking through include dose optimization, dietary adjustments, exercise modifications, and in some cases, medication switching

While PT-141 also causes nausea in many, its overall benefit-risk seems better than what apomorphine offered

PMID 15459602

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Angiogenesis 7(3):193201 Yang R et al (2002) Exaggerated hypotensive effect of vascular endothelial growth factor in spontaneously hypertensive rats

This dual activation leads to a higher peak GH level than either peptide alone