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This pronounced weight loss effect, combined with improvements in glycemic control and cardiometabolic parameters, positions tirzepatide as a valuable intervention for obesity-related comorbidities, including obstructive sleep apnea

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In that work, co-immunoprecipitation analysis showed reduced binding between caveolin-1 and eNOS, an interaction normally responsible for limiting eNOS activity

In vitro , ICA effectively attenuated the IL-1 induced suppression of SLC7A11 and GPX4 expression in SW1353 cells, restored intracellular levels of ROS, lipid peroxides, and MDA, and significantly reduced erastin induced ferroptosis