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Its mechanism involves stimulating natural GH release specifically to reduce visceral adipose tissue, with research originally focused on HIV-associated lipodystrophy

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[ref] Additionally, animal research shows that berberine promotes the production of BH4 through interaction with gut bacteria

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Additionally, the expressions of GLUT1, GLUT6, and Ki-67 were downregulated, while SREBP2 expression increased in the treated group (Fig

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