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Patient B: Jennifer, 43 Starting weight: 242 pounds Height: 57 Exercise approach: No resistance training, some walking, protein intake around 50-60g daily After 11 months: Weight: 168 pounds (74 pounds lost) Body fat: 34% (down from 43%) DEXA scan: 47 pounds fat lost, 27 pounds muscle lost Resting metabolic rate: Dropped 280 calories from baseline Clothing size: 22 to 12 Strength: Not assessed (no baseline) Jennifer looked deflated

When appetite suppression becomes effective, patients naturally consume fewer calories without fighting intense hunger, eliminating the exhaustion that accompanies restrictive dieting

Broader access to semaglutide therapy may be supported by clinically suitable alternative formulations if pharmacokinetic comparability with the reference product is established

Both medications can cause side effects such as nausea, vomiting, and gastrointestinal discomfort