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Specifically, reduced GLP-1 was associated with altered expression of the pro-inflammatory macrophage marker CD86

Vet Sci

doi: 10.3390/antiox13020197 224 GorrepatiKKumarAAhammed ShabeerTPKhanZSatputePAnandhanSet al

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Furthermore, after acute UVB exposure, melanocytes in VDR-deficient mice exhibited reduced proliferative activity (PCNA/TYRP1), increased numbers of cells positive for the DNA damage marker CPD, and a significantly elevated apoptotic index (TUNEL/TYRP1), highlighting the protective role of VDR in mitigating UVB-induced genotoxic stress and sustaining melanocyte viability [134]