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10.1186/bcr1275 [DOI] [PMC free article] [PubMed] [Google Scholar] Dixit V, Chaubey KK, Dayal D, Chole PB, Manjunath BT, Bachheti RK, Gupta PC, Bachheti A, Worku LA (2025) Natural products in aging: cellular mechanisms and emerging therapeutics for age-related disorders

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The peptide appears to maintain organ function under stress conditions through nitric oxide system modulation and vascular protection mechanisms

Certain retained components of various cell death pathways such as Fas (CD95)/Fas ligand (FasL, CD95L) signaling, caspase-3, caspase-8, or RIPK1/RIPK3 (receptor-interacting serine/threonine-protein kinase 3)/MLKL (mixed lineage kinase domain like pseudokinase) axis can be considered a heritage of the erythroid lineage cells

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Exposure to sunlight will indirectly affect the whitening process since it increases the melanin pigments in the skin, thus, might delay the whitening process