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Preclinical safety profiles show no acute organ toxicity at doses far exceeding proposed human doses

This is consistent with GHK-Cus known role in upregulating collagen synthesis in dermal fibroblasts, a mechanism confirmed in a comprehensive review in Biomolecules documenting GHK-Cus influence across more than 4,000 human genes involved in tissue remodeling and repair

described as transient Nausea community sources most commonly report this in the first 2-3 injections, described as dose-dependent Headache occasionally self-reported

the FDA advisory committee then voted against permitting their compounding, leaving them restricted (source)