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While non-steroidal MRAs have not yet been investigated in type 1 diabetes, based on their observed benefits in type 2 diabetes and their mechanism of action, similar kidney-protective effects are anticipated, emphasising the need for dedicated studies with finerenone in people with type 1 diabetes and CKD, including their use in combination with other repurposed therapies such as SGLT2i and GLP1-RAs
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In this mini-review, we highlight past and present progress in the translational research of GLP-1 and glucagon co-agonism
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