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Topol has been a loud voice of caution against the untested drugs

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The Q statistics were used to evaluate the statistical heterogeneity between the trials, and a P value of less than 0.1 or an I 2 value greater than 50% was considered to indicate significant heterogeneity between the studies

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Competing interests: The authors have declared that no competing interests exist

Organizations focused on diabetes management emphasize the importance of screening patient history before initiating therapy