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Clinical trial data from the NEJM Phase 2 study showed that gastrointestinal events were predominantly mild to moderate, occurred primarily during dose escalation, and were partially mitigated by starting at 2mg rather than 4mg

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What makes BPC-157 distinctive among research peptides is a combination of three properties rarely found together: it has no sequence homology to any other known peptide, it is completely stable in human gastric acid for at least 24 hours (unlike most growth factors and peptide analogues, which are rapidly degraded), and it remains active across an exceptionally broad effective dose range from nanogram to microgram per kilogram bodyweight in pre-clinical models without any known toxic dose having been established in animal studies to date

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