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longum has been shown to modulate the host immune transcriptome and suppress proinflammatory cytokine expression

[6] [7] Mutations in GPX4 cause spondylometaphyseal dysplasia

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doi: 10.1128/AEM.02288-17 47 NishioJSatoHWatanabeEMasuokaHAokiKKawazoeMet al

METHODS: The phase 3a, 68-week REDEFINE 1 trial randomized adults without diabetes with body mass index 30 kg/m 2 , or 27 kg/m 2 with 1 obesity-related complication, to once-weekly CagriSema 2.4 mg/2.4 mg, semaglutide 2.4 mg, cagrilintide 2.4 mg, or placebo, plus lifestyle intervention

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