Some people who eat little or no animal foods such as vegetarians and vegans
Studies have shown that whole body retention of vitamin B12 at 14 days in elderly subjects is comparable to that in younger individuals, indicating that age does not significantly affect vitamin B12 absorption
The receptor overlap creates compounding effects that dramatically increase side effect risk without proportional benefit
Moreover, the presence of sodium and chlorine ions may in some cases affect the stability of peptides sensitive to the ionic strength of the solution
Concurrent administration of pyridoxine with these medications has been reported to lower their therapeutic levels, so monitoring and dosage adjustments of the anticonvulsant might be required if high-dose vitamin B is given
Although short-term use of unapproved peptides appears to be mostly safe, the larger concern lies with downstream side effects that we just dont know about, says Cushman