dr jimmy gutman glutathione & Cancer Jimmy Gutman MD (@drjimmygutman) •

Set the bench correctly first

If you're shopping for a guy on TRT, you're probably getting a lot of unhelpful suggestions

For cagrilintide, the structural choices made during its development directly determine its behavior in preclinical assays: how long it persists in pharmacokinetic models, how effectively it binds target receptors, and whether it aggregates in solution before reaching those receptors

Akyuz E, Polat AK, Eroglu E et al (2021) Revisiting the role of neurotransmitters in epilepsy: an updated review

By replenishing B12 stores, it ensures that key bodily processes, including nerve function and cellular energy metabolism, operate effectively

Ex vivo analysis of mitochondria derived from rats subjected to ballistic injury revealed decreases in the enzymatic activity of pyruvate dehydrogenase and glutamate dehydrogenase, which reduce input from glucose and glucogenic AAs into the citric acid cycle (reduced CoA-SH and acetyl-CoA concentrations), at 24 h after injury [72, 75]