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10.1038/379069a0 121 VahlT

Second-line or augmentation strategies for treatment resistance include dopamine antagonists and glutamatergic agents (9), but these are effective in less than half of serotonin reuptake inhibitor (SRI)-resistant OCD (3)

The lack of difference in the growth of AgRP GHR KO mice, as compared to control mice, is interesting since previous studies suggested that NPY plays a role regulating GH secretion and consequently somatic growth 36,37,38

And people with less weight to lose have even less need of large doses

While that works for many, studies in older adults indicate that taking a bit more may yield good results for muscle and bone health

Understanding GLP-1 & GIP Medications What Are GLP-1 Receptor Agonists