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doi: 10.3389/fphar.2020.579944 Received 03 July 2020 Accepted 15 September 2020 Published 07 October 2020 Volume 11 - 2020 Edited by Leonello Fuso, Catholic University of the Sacred Heart, Italy Reviewed by Stephen C

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Their benefits now extend well beyond glycemic control and weight loss, with growing evidence supporting their use in the management of steatosis liver disease, obstructive sleep apnea, cardiovascular disease, and chronic kidney disease

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Central Nervous System Effects : Perhaps most intriguingly, research has revealed that the anti-inflammatory effects of GLP-1 receptor agonists require GLP-1 receptors in the central nervous system, not just in blood or endothelial cells