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If confidence in this approach depends on the belief that it has already been studied at scale, that belief is not supported by current evidence

The Breakthrough Prize carries the highest monetary award of any prize in the life sciences $3 million and is being presented today at an award ceremony in Los Angeles.

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Further, the reduction in colony formation upon silencing LDHB could be partially rescued by supplementation with the small molecule ferrostatin-1 (FER1), a lipid hydroperoxyl radical scavenger, which inhibits iron-dependent lipid peroxidation 13,34 (Fig