2,4 The results demonstrate survodutides potential to reduce weight and therefore improve metabolic health in two distinct populations: adults living with obesity or overweight, without type 2 diabetes (SYNCHRONIZE-1), 2 and adults with overweight or obesity with metabolic dysfunction-associated steatotic liver disease (MASLD) with evidence of inflammation and or fibrosis (SYNCHRONIZE-MASLD)
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doi: 10.1038/414782a Summary Keywords Akkermansia muciniphila , type 2 diabetes mellitus, gut microbiota, metabolic diseases, endotoxemia, prebiotics Citation Li J, Yang G, Zhang Q, Liu Z, Jiang X and Xin Y (2023) Function of Akkermansia muciniphila in type 2 diabetes and related diseases
The role of l-carnitine in mitochondria, prevention of metabolic inflexibility and disease initiation