In reality, they're closely linked and share the same brain pathways, a connection explored in research by Morales on integrating the brain's homeostatic and reward-based hunger systems
In type 2 diabetes, the incretin effect diminishes because of impaired GLP-1 secretion and decreased GIP activity
Cell debris was removed by centrifugation at 4,400 g at 4 C for 30 min
The clearest demonstration of aberrant gut microbiota-host interaction in obesity comes from studies in germ-free mice, demonstrating that the obese phenotype is transmissible from DIO mouse donors to lean recipients and vice versa 9,14,15
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