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Excessive Vitamin B12 May Increase the Risk of Lung and Colon Cancer A large-scale 2017 study published in the Journal of Clinical Oncology found that males who supplemented with megadoses of vitamins B6 and B12 had a 30% to 40% increased risk of lung cancer compared to individuals who did not supplement

For customized products, the MOQ may be higher

This means they can't absorb B12 from food, though they can from a supplement

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Cyanocobalamin injection, USP: Package insert

Conclusion For people at a higher risk of health-related issues connected to a vitamin B12 deficiency, the benefit of B12 shots is they significantly reduce symptoms