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Formation of N-nitrosamine drug substance related impurities in medicines: a regulatory perspective on risk factors and mitigation strategies

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113 N-acetylcysteine N-acetylcysteine (NAC), a free radical-quenching compound made from the sulfur-containing amino acid cysteine, has been shown to reduce inflammation and oxidative stress, stabilize proteins and DNA, promote mitochondrial resilience, support antiviral immune activity, and promote vascular health

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-Non-classical sites of hormone expression were identified, including secretin in plasmacytoid dendritic cells

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Astrocytes showed 381 DEGs, with 22 Fr-DEGs identified (Fig

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