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In addition, CD8 + T cells sourced GzmK, a tryptase-like protease, can cleaving fibroblasts produced complement proteins to activate the complement cascade and drive RA inflammation (Wang et al., 2022)

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used the NLS-TAT peptide to deliver the hTGF-3 plasmid into precartilaginous stem cells, which promotes chondrogenesis of these cells [27]

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