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The critical comparison is speed: retatrutide achieved comparable or superior weight loss in approximately half the time required by semaglutide, and in roughly two-thirds the time required by tirzepatide

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A review of Diabetic Gastroparesis found that the class of drugs known as glucagon-like peptide 1 (GLP-1) receptor agonists such as dulaglutide (Trulicity) may exacerbate the symptoms of diabetic gastroparesis and therefore are not recommended for individuals experiencing symptoms of gastroparesis

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