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Thompson JA, Larion S, Mintz JD, Belin De Chantemle EJ, Fulton DJ, Stepp DW

In the STEP 1 to STEP 4 studies, dose decreases occurred in between 3% and 9% of semaglutide patients and between 2% and 4% of placebo patients, and dose increases occurred in between 4% and 7% of semaglutide patients and between 4% and 9% of placebo patients (Table 34)

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The effectiveness of Semaglutide GLP-1 in non-diabetics is primarily attributed to its mechanism of action, which involves mimicking the hormone GLP-1 to regulate appetite and calorie intake effectively

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