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They typically involve higher costs and require in-person visits but may provide a more thorough clinical evaluation

Among them, two of the patients facing hypoglycemia in the semaglutide group were on combination therapy with sulfonylurea (glimepiride), and two of them were on combination therapy with premixed insulin

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Anyone considering berberine alongside GLP-1 therapy should monitor blood glucose closely and work with a healthcare provider

PubMed , Bone , vol

Prof Sir John Hardy , Group Leader at the UK Dementia Research Institute at UCL, said: There is no mechanistic evidence linking Alzheimers disease and type 2 diabetes (see Hardy et al 2022) and on that basis, it would be expected that the anti-diabetic GLP-1 agonist would have no beneficial effect in AD