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(2010) Effect of 2-y n3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: a randomized, double-blind, controlled trial

The Alpha-Tocopherol, Beta-Carotene (ATBC) trial showed that using BC supplements was linked to an 18% higher chance of developing lung cancer

BMJ 369:m2382

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It also contains high dose Vitamin C, which can boost the immune system and support skin health

Therefore, the development of this vaccine in clinical trials could be more complicated than in in vivo experiment, given the diverse physiological functions of GPNMB in normal cells