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This cellular mechanism appears fundamental to the peptides observed healing effects across diverse tissue types

Acknowledgements We are grateful for the support from the Laboratory Animal Center at National Taiwan University, College of Medicine and Flow Cytometric Analyzing and Sorting Core of the First Core Laboratory, National Taiwan University College of Medicine for providing the service

Controlled studies for treatments that address mitochondrial disorders include l-carnitine and a multivitamin with various mitochondrial supplements

Glutathione acts to inhibit the process of melanogenesis either by directly inhibiting the enzyme tyrosine kinase that catalyzes it, or indirectly by means of its antioxidant properties

10.1111/and.13470 43

Furthermore, NAC has been shown to influence redox-sensitive cell-signalling and transcription pathways, such as NF- B (which regulates proinflammatory genes), the p38, ERK1/2, SAPK/JNK, c-Jun, and c-Fos pathways, among others, in a wide variety of different systems [17, 21, 22]