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It is unclear whether the enrichment of M2 macrophages represents an attempt to resolve existing lipedema-associated inflammation (in line with their typical role of healing) or whether the macrophages are pro-fibrotic and promoting dysfunctional repair mechanisms leading to inflammation

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If you are considering whether lower BMI thresholds may apply to you based on your ethnic background, discuss this with your GP, who can refer to relevant NICE public health guidance

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Provide regular training updates to inform personnel about changes and updates in regulations