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The Biochemical Journal 446, 333348
2016 tarihli bir aratrma incelemesine gre yumurtalar, GLP-1 salglanmasnda rol oynayabilen zengin bir protein ve tekli doymam ya kaynadr
Since GLP-1-induced insulin secretion requires glucose metabolism, we aimed to address the hypothesis that GLP-1 receptor (GLP-1R) signalling can modulate glucose uptake and utilization in -cells
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In patients with DM2 the incretin response is diminished, but the insulinotropic effect of GLP-1 is conserved.28 Under normal conditions GLP-1 has a short half-life (approximately 2 min), as it is rapidly degraded by dipeptidylpeptidase 4, so GLP-1 analogues resistant to this enzyme have been developed for the treatment of DM2.29 arGLP-1: glucagon-like peptide 1 receptor agonist
doi:10.1158/1940-6207.Capr-08-0081 117
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