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Peptide therapy is popular for its relatively low side effects

Specifically, chronic inflammation in RA can lead to long-term changes in the central nervous system (CNS), resulting in heightened pain sensitivity (hyperalgesia) and pain from non-painful stimuli (allodynia) (Sa et al., 2020

IGF-1-RIT1-Akt-Sox2 pathway plays a key role in IGF-1-induced neurogenesis, cellular proliferation, and gene expression in hippocampus neurons [39]

Yin J, Wei L, Wang N, Li X, Miao M

no clinical trial data exist for this pairing, though their complementary amylin and incretin-based mechanisms provide a theoretical scientific rationale

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