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Why did the investigators wash out the drug for 2 months after the primary outcome

Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product

The unfortunate truth is that big risk signals (lets say the kind you get from drinking antifreeze) can be spotted from the anecdotal experience of people in the world just trying things, but small-but-serious risk signals (lets say cardiovascular disease with tofacitinib) are really hard to identify without a proper trial or a proper observational study

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