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Mice were treated subcutaneously at the indicated doses with 5 l per g body weight of either Vehicle, Lani (CAS: 927961-18-0, MedChemExpress), semaglutide, GLP-1Lani, GLP-1Tesa, GLP-1GIP, GLP-1GIPTesa, GLP-1GIPLani, or co-administration of either GLP-1GIP plus Lani or GLP-1Lani plus acyl-GIP (Extended Data Fig

Authorship All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the work as a whole, and have given their approval for this version to be published

His approach emphasizes nutrition, physical activity, and behavioral support for long-term results

Over 56 weeks, participants taking liraglutide 3 mg lost 8% of body weight from baseline (vs

This allows stacking without redundancy if injection timing is staggered by 1224 hours