L-Carnosine concentrates in the lens of the eye where it is reported to work to prevent cataracts
It arises due to a combination of genetic and lifestyle factors that contribute to defective production of insulin from pancreatic beta cells, and/or resistance to its uptake by insulin receptors located in peripheral and central tissues in the body
Allergen Warning: May contain traces of milk, egg, soy, gluten, shellfish and seafood
They should be considered adjuncts, not replacements, to lifestyle and medical care
10.1016/s0022-2143(96)90028-1 39 DietzM
One potential mechanism is the Nrf2-ARE pathway, which induces a phase 2 detoxification response that promotes disruption of Nrf2-Keap protein interactions, translocation of Nrf2 to the nucleus, and regulation of target gene expression through the ARE, enhancing cellular defense against oxidative damage (Sharma et al., 2010)