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Cytokine modulation by GLP-1
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2022, Carganico and Papini 2011) Furthermore, Boc group requires strong acidic conditions such as trifluoroacetic acid (TFA), whereas Fmoc group is removed under basic conditions such as Piperidine, which can induce undesirable side reactions, including aspartimide and piperidide formation (Carganico and Papini 2011, Ralhan et al
In the same mouse model, MEDI4166 also demonstrated efficient glucose control following a GTT performed 10 days after a single administration (Supplementary Fig
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