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A reduction of NAD+ within the body can lead to a decrease in the amounts of energy produced in the mitochondria

In a study with 70 Chinese patients ( n = 70) with acute lymphoblastic or acute myeloid leukemia who were receiving chemotherapy, those receiving silymarin (420 mg/day) in combination with diammonium glycyrrhizinate had a higher percentage of patients reporting no or mild DILI than those receiving only diammonium glycyrrhizinate (Baskaran & Sabina, 2017

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