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doi: 10.1016/S0092-8674(00)81558-5

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The in vivo model utilized 10-week-old male C57BL/6 mice that were housed in environmentally controlled conditions with a 12-hour dark-light cycle, receiving standard laboratory chow and water ad libitum

1997;112:A400

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The mechanisms of action for butyrate are due to the fact that it helps regulate gene expression, supports intestinal homeostasis and energy metabolism, and is an anti-inflammatory (Liu et al., 2018)