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Neither spinalization nor bilateral transection of pelvic or dorsal penile nerves impaired the facilitator activity of intravenous Melanotan II, but removal of the lumbar paravertebral sympathetic chain abolished the effect, indicating recruitment of both central and peripheral melanocortin pathways depending on route of delivery

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Storage : Solutions for infusion should be used within 24 hours, if stored below 25 C, or 48 hours if stored refrigerated (2 C to 8 C), from the time of preparation

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Dosage Each pen delivers approximately 1 mg per 10 clicks, allowing precise and adjustable dosing