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Phase Early escalation Weeks 5-8 Weekly Dose 4 mg Notes Increase by 2 mg every 4 weeks

A great deal of work focusing on the regulation of uPA activity in the initial stage of liver regeneration is underway

The kinase fusion genes are similar to those that occur in Spitz nevi, but the histopathologic features of congenital nevi with Spitz nevus initiating mutations and their natural history has yet to be determined