glp-1 in obesity Simplified summary of the biological actions of GIP and as Weight loss with GLP-1 medicines

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J Biol Chem 280, 3950539509, 10.1074/jbc.M506096200 (2005)

The ceiling exists

Wellness 13 (2), 649658

Research published in JCI Insight describes tirzepatide as an "imbalanced and biased dual agonist," meaning it actually engages the GIP receptor more potently than the GLP-1 receptor

"Theres also reason to believe with lifestyle improvement which includes better sleep, eating better and exercise you might wind up in a healthier state than just weight loss with the medications." If lifestyle modification doesnt work and parents are interested, he sometimes prescribes medication