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When HIF-1 is not hydroxylated, and is thus not targeted for degradation by ubiquitylation, it migrates to the nucleus leading to an increase in the transcription of HIF-1 target genes
Conclusions There appears to be no significant marginal benefit in terms of all-cause mortality, heart failure, unstable angina, or myocardial reinfarction in the setting of acute MI for oral L-carnitine maintenance doses of greater or less than 3 g per day
10.1007/s12035-016-0088-8 40 CuiJ
M.VercelliC
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