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Its strong antioxidant properties help protect skin from UV damage, support retinal health, and enhance muscle endurance and recovery

The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4

Medicine Reports 22 (3), 24242432

Consequently, nonpalmitoylated PD-L1 is subjected to increased ubiquitination and subsequent lysosomal degradation, which ultimately remodels the anti-tumor immune response [168]

Impaired methylation can mean that a huge range of important molecules may not be efficiently produced

In macrophage models, -KG promotes JMJD3-mediated H3K27me3 demethylation, thereby favoring the expression of M2-related genes, whereas succinate accumulation can inhibit demethylase activity and sustain a pro-inflammatory transcriptional state (38)