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GLP1RAs can inhibit neutral lipid accumulation, ROS generation, and (NADPH oxidase 4) NOX-4 expression in rat cardiomyocytes, thereby migrating interleukin-1 (IL-1 ) induced ROS production [57]

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Its triple receptor activity makes it particularly valuable for mechanistic investigations involving glucose regulation, nutrient utilization, metabolic flexibility, and energy expenditure

Hamasaki, H

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