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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Ling W., Huang Y.-M., Qiao Y.-C., Zhang X.-X., Zhao H.-L

The introduction of the R17 Cagri- E14 Cagri intra-peptide ionic lock energetically favours the formation of a predominant bypass conformation at the CTR, which, together with the P37 substitution and the effects induced by the N-terminal acylation, likely underlies its improved potency over rAmy at this receptor

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AOD-9604 has not been approved by the FDA or any major regulatory body for human therapeutic use