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This compounds across multiple exposures, which is why strict cold chain discipline matters from the moment of reconstitution

doi: 10.3390/ijms251910795

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13.3.4 GI and intestinal side effects Notwithstanding their well-documented health benefits, the use of probiotic supplements requires careful evaluation, particularly in immunocompromised individuals, pregnant women, critically ill neonates, and patients in postoperative recovery

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